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Calcipressin 1/DSCR 1钙调神经磷酸酶调节蛋白1抗体(唐氏综合征候选区域蛋白1样蛋白1),抗体质量可靠,订购
Calcipressin 1/DSCR 1钙调神经磷酸酶调节蛋白1抗体(唐氏综合征候选区域蛋白1样蛋白1)请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:
钙调神经磷酸酶调节蛋白1抗体(唐氏综合征候选区域蛋白1样蛋白1)英文名称:
Anti-Calcipressin 1/DSCR 1货号:bs-11541R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 23kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:DSCR1 protein influences cardiac and nervous system development (1). DSCR1 is abundant in the brain, heart, and skeletal muscle. Overexpression of DSCR1 may play a role in the pathogenesis of Down syndrome, in particular mental retardation and/or cardiac defects. DSCR1 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Human DSCR1 maps to gene locus 21q22.1-q22.2.Function : Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.Tissue Specificity : Highly expressed heart, brain and skeletal muscle. Also expressed in all other tissues.Similarity : Belongs to the RCAN family.