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FDFT1法尼基二磷酸法尼基转移酶1/鲨烯合成酶抗体,抗体质量可靠,订购
FDFT1法尼基二磷酸法尼基转移酶1/鲨烯合成酶抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:
法尼基二磷酸法尼基转移酶1/鲨烯合成酶抗体英文名称:
Anti-FDFT1货号:bs-11517R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 48kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:Several proteins mediate the biosynthesis of cholesterol. The first specific step in the cholesterol biosynthetic pathway is the conversion of transfarnesyl-diphosphate to Squalene, which is catalyzed by the endoplasmic reticulum membrane-associated enzyme Squalene synthetase, also designated Squalene synthase and Farnesyl-diphosphate farnesyltransferase. Squalene synthetase is located at a branch point in the mevalonate pathway and is also involved in isoprenoid biosynthesis. Squalene epoxidase, also designated Squalene monooxygenase, is a multi-pass microsomal membrane-associated enzyme that catalyzes the first oxygenation step in sterol biosynthesis and most likely functions as one of the rate-limiting enzymes in this pathway. Squalene epoxidase may form a complex with Squalene synthetase.Function : Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.Subcellular Location : Endoplasmic reticulum membrane.Similarity : Belongs to the phytoene/squalene synthase family.