Anti-VAX2视神经视网膜相关蛋白VAX2抗体

本公司提供科研VAX2视神经视网膜相关蛋白VAX2抗体，抗体质量可靠，订购VAX2视神经视网膜相关蛋白VAX2抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：视神经视网膜相关蛋白VAX2抗体
英文名称：Anti-VAX2
货号：bs-11497R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 31kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：VAX2 is a 290 amino acid homeobox protein that plays a crucial role in development of the eye, particularly in the specification of the ventral optic vesicle and in establishment of a correct dorsoventral pattern. VAX2 acts as a transcription factor with VAX1 to cooperatively regulate retinal differentiation, neuroepithelial cell proliferation and axial polarization in the retina. Together, VAX1 and VAX2 repress transcription of Pax-6, a strong inducer of retinal development. VAX1 and VAX2 localize to the nucleus and contain one homeobox DNA-binding domain each.Function : VAX2 belongs to the EMX homeobox family and contains 1 homeobox DNA-binding domain. VAX2 gene has high sequence similarity to VAX1 gene and is almost exclusively expressed in the ventral portion of the retina during development. It may play an important role in morphogenetic processes underlying the correct development of the eye, particularly in the establishment of a correct dorsoventral pattern and may be a regulator of axial polarization in the retina.Subcellular Location : Nuclear