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PAPSS1腺苷酸硫酸激酶1抗体，抗体质量可靠，订购
PAPSS1腺苷酸硫酸激酶1抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：
腺苷酸硫酸激酶1抗体英文名称：
Anti-PAPSS1货号：bs-9029R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 69kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, hrs, cow, dog, Rb
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. Also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells.Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetases (PAPS synthetase or PAPSS), also designated sulfurylase kinase (SK), are important for sulfate assimilation in the sulfur metabolism pathway. PAPSS proteins are bifunctional enzymes with APS kinase and ATP sulfurylase activity, which mediate two steps in the sulfate activation pathway. The PAPSS proteins belong to the APS kinase family and to the sulfate adenylyltransferase family of proteins. In mammals, PAPSS proteins are the sole source of sulfate. PAPSS 1, which is involved in biosynthesis of sulfated L-selectin ligands in endothelial cells, is regulated by chlorate inhibition. It is expressed primarily in pancreas, liver, testis, thymus, kidney, prostate, ovary and small intestine. Tissue Specificity : Expressed in testis, pancreas, kidney, thymus, prostate, ovary, small intestine, colon, leukocytes and liver. Also expressed in high endothelial venules (HEV) cells and in cartilage.Similarity : In the N-terminal section; belongs to the APS kinase family.In the C-terminal section; belongs to the sulfate adenylyltransferase family.
