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MyoGEF肌球蛋白相互作用G蛋白交换因子抗体,抗体质量可靠,订购
MyoGEF肌球蛋白相互作用G蛋白交换因子抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:
肌球蛋白相互作用G蛋白交换因子抗体英文名称:
Anti-MyoGEF货号:bs-7756R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 89kDa
纯化方法:affinity purified by Protein A
交叉反应:Human
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:MyoGEF functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.