Drummond Scientific has a long and outstanding history in the manufacturing of microinjection apparatus. Several years ago we became aware that our 10uL positive displacement microdispenser was being modified to inject Xenopus oocytes. We modified this unit by redesigning the microdispenser to eliminate any tip movement caused by plunger rotation. Further modifications seemed uneconomical which prompted a complete redesign. Drummond developed a positive displacement motorized unit which was capable of repetitively dispensing precisely 46 nL., a volume optimized for oocyte injection. This was to be the first Nanoject. The next model offered the scientist a variable volume, ranging from 4.6 nL. to 73.6 nL. Hence, the Nanoject Variable. The introduction of the Nanoject II offers volumes ranging down to 2.3 nL. and up to 69nL. with a higher torque motor. This new motor is quieter and smoother in operation further reducing tip movement. The development of new collet configuration will hold the micropipet more securely and thereby reduce air infiltration and oil leakage. The two speed fill/inject mode will allow the user to fill and inject at half speed facilitating the use of smaller micropipets. The handling of more viscous samples will also be improved. All factors which enhance the precise delivery of sample. Although previous models are excellent for Xenopus injections, the smaller tips and smaller injection volume may allow the user to perform injections into other specimens that previously could not be performed with older models. Positive displacement technology and the use of precision micropipets, eliminates the need for tedious calibration when the viscosity of the samples change. Contaminates in the sample do not hinder or change the injection volume as with some other injectors. The Drummond Nanoject II Auto-Nanoliter Injector is specifically designed to perform ultra-delicate nanoliter injection procedures into cells. Each Nanoject II Auto-Nanoliter Injector comes complete with 200 borosilicate capillaries that can be pulled to the required tolerance together with a back filling needle and maintenance kit. Drummond Scientific在显微注射设备的制造方面拥有悠久而的历史。几年前,我们意识到我们的10uL正位移微分配器正在被修改以注射非洲爪蟾卵母细胞。我们通过重新设计微分配器来修改此装置,以消除由柱塞旋转引起的任何移动。 进一步的修改似乎是不经济的,这促使完全重新设计。 Drummond开发了一种正排量电动装置,能够重复精确分配46 nL,这是一种针对卵母细胞注射优化的体积。这是个Nanoject。 下一个模型为科学家提供了一个可变容积,范围从4.6 nL。到73.6 nL。因此,Nanoject变量。 Nanoject II的推出可提供低至2.3 nL的体积。高达69nL。使用更高扭矩的电机。这种新型电机操作更安静,更平稳,进一步减少了运动。新夹头配置的发展将使微量移液管更加牢固,从而减少空气渗透和漏油。双速填充/注入模式将允许用户以半速填充和注入,从而有助于使用更小的微量移液管。处理更粘稠的样品也将得到改善。所有促进样品精确输送的因素。 虽然之前的型号非常适合非洲爪蟾注射,但较小的吸头和较小的注射量可能允许用户对以前无法用旧型号进行的其他样品进行注射。 正位移技术和精密微量移液管的使用,无需在样品粘度发生变化时进行繁琐的校准。与其他一些注射器一样,样品中的污染物不会妨碍或改变注射量。 Drummond Nanoject II Auto-Nanoliter注射器专门设计用于对细胞进行超精细纳升注射程序。每个Nanoject II Auto-Nanoliter注射器都配有200个硼硅酸盐毛细管,可以与背部填充针和维护套件一起拉至所需的公差。 |