仪器网产品库 FoxP3/Scurfin Polyclonal Antibody

FoxP3/Scurfin Polyclonal Antibody

品牌：Cayman
型号： 13739
产地：加拿大
价格：面议
供应商：上海超研生物科技有限公司

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产品信息 保质期： 1年供应商：超研生物保存条件： -20度数量：大量规格： 1 ea Description Antigen: synthetic peptide corresponding to the exon 2 deletion site was used as immunogen · Host: rabbit · Application(s): IHC and WB · One of the many immunotolerance mechanisms that the immune system has developed to distinguish between self and non-self antigens are regulatory T-cells or Tregs. Several elegant experiments using transgenic mice and retrovirus-mediated over-expression studies have led to the identification of FoxP3, a transcription factor, as a specific molecular marker essential for the development and function of Tregs. The primary evidence regarding the involvement of FoxP3 in the development of Tregs was provided in patients suffering from IPEX, a rare and fatal human autoimmune disease. The emergence of Tregs and the role of FoxP3 as a critical player in the negative control of various normal and pathological immune responses holds great promise for the development of novel therapies for autoimmune diseases. Formulation 100 µg of protein G-purified IgG in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide Stability 1 year Storage -20°C Shipping Wet ice in continental US; may vary elsewhere Specificity Bovine FoxP3/Scurfin + Chicken FoxP3/Scurfin + Equine FoxP3/Scurfin 温馨提示：不可用于临床ZL。

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