产品名称: | TNF-alpha Antibody |
说明书: | 【点击查看详细说明及参考图片】 |
货号: | 251900 |
规格: | 0.1 mg |
产品描述: | Tumor necrosis factor alpha (TNF-alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces cell death of certain tumor cell lines. It is a potent pyrogen causing fever by direct action or by stimulation of IL-1 secretion, and therefore found in cachexia accompanying diverse cancers and infections. Genetic variations in TNF are associated with susceptibility to psoriatic arthritis and to HBV infection. |
克隆类型: | Rabbit Polyclonal Antibody |
亚型: | Rabbit Ig |
免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human TNF-alpha. |
适用物种: | H, M, R, P, Hs, D, Ca, Sh |
应用范围: | E, WB, IHC |
应用说明: | E: 1:1,000-1:5,000; WB: 1:500-1:1,000; IHC: 1:1,000-1:2,000 |
别名: | Tumor necrosis factor; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; Cachectin; TNF; TNFA; TNFSF2 |
形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2 % BSA with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography. |
保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
参考文献: | [1] Hwang J-H. et al. 2013. PLoS ONE. 8(4):e60730. PMID# 23637762. [2] Carta A et al. 2011. Neuroscience. 194:250-261, PMID: 21839812. [3] Pisanu A et al. 2014. Neurobiol Dis. 71: 280-91. PMID# 25134730. |