CD274 Antibody_CD274抗体

抗体名： CD274 Antibody 抗体英文名： CD274 Antibody 靶点： CD274 浓度： 见详细说明信息 应用范围： E, WB, IHC 宿主： Rabbit 供应商： Abbiotec 数量： 大量 级别： 超纯 目录编号： 251474 抗原来源： KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD274. 保质期： 1-2年 适应物种： H, M, R 标记物： 见下方详细说明 克隆性： 多克隆 保存条件： Store at -20°C. 形态： Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography. 亚型： Rabbit Ig 免疫原： KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD274. 规格： 0.1 mg

CD274 Antibody产品详细介绍：

产品名称：	CD274 Antibody
说明书：	【点击查看详细说明及参考图片】
货号：	251474
规格：	0.1 mg
产品描述：	CD274 is involved in the costimulatory signal transduction cascade which is essential for T-cell proliferation. CD274 is also involved in the production of IL-10 and interferon gamma. Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. PDL-1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PDL-1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts.
克隆类型：	Rabbit Polyclonal Antibody
亚型：	Rabbit Ig
免疫原：	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD274.
适用物种：	H, M, R
应用范围：	E, WB, IHC
应用说明：	E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
别名：	B7-H1; PDL1; CD274; Programmed death ligand 1; Programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; B7 homolog 1; B7H1; PDCD1L1; PDCD1LG1
形态：	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
保存条件：	Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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