产品名称: | Mucin-1 Antibody |
说明书: | 【点击查看详细说明及参考图片】 |
货号: | 251746 |
规格: | 0.1 mg |
产品描述: | CA15-3 (MUC-1) is a type I transmembrane protein expressed in the apical membrane of highly polarized epithelial cells. CA15-3 is also overexpressed in epithelial tumors, such as breast or ovarian cancer. CA15-3 is composed of alpha and beta subunits. The alpha subunit has cell adhesive properties, whereas the beta subunit modulates signaling in the SRK, ERK, and NF-kappa B pathways. CA15-3 is used as a serological clinical marker of breast cancer to monitor response to breast cancer treatment and disease recurrence. |
克隆类型: | Mouse Monoclonal Antibody |
亚型: | Mouse IgG1 |
免疫原: | Human milk fat globule membranes. |
适用物种: | H |
应用范围: | E, IHC |
应用说明: | IHC: 1:100-1:500; E: 1:500-1:1,000 |
别名: | CA15-3; CA15.3; CA153; Carbohydrate antigen 15-3; Cancer antigen 15-3; Mucin-1; MUC-1; Polymorphic epithelial mucin; PEM; PEMT; Episialin; Tumor-associated mucin; Carcinoma-associated mucin; Carcinoma-associated mucin; Tumor-associated epithelial membrane antigen; EMA; H23AG; Peanut-reactive urinary mucin; PUM; Breast carcinoma-associated antigen DF3; CD227; MUC1; PUM; Krebs von den Lungen-6; KL-6 |
形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
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