产品名称: | PDCD4 Antibody |
说明书: | 【点击查看详细说明及参考图片】 |
货号: | 252075 |
规格: | 0.1 mg |
产品描述: | Programmed cell death protein 4 (PDCD4) inhibits translation initiation and cap-dependent translation. PDCD4 excerts its function by hindering the interaction between EIF4A1 and EIF4G. PDCD4 inhibits the helicase activity of EIF4A and modulates the activation of JUN kinase. PDCD4 down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription.PDCD4 inhibits tumor promoter-induced neoplastic transformation. |
克隆类型: | Rabbit Polyclonal Antibody |
亚型: | Rabbit Ig |
免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PDCD4. |
适用物种: | H, M, R |
应用范围: | E, WB, IHC |
应用说明: | E: 1:10,000-1:50,000; WB: 1:100-1:1,000; IHC: 1:100-1:500 |
别名: | Programmed cell death protein 4; Nuclear antigen H731-like; Neoplastic transformation inhibitor protein; Protein 197/15a; PDCD4; H731 |
形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
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