Rosiglitazone (potassium salt),potassium,5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidin-3-ide-2,4-dione,316371-84-3

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试剂描述：

产品名称：Rosiglitazone (potassium salt)

产品别名：5-​[[4-​[2-​(methyl-​2-​pyridinylamino)ethoxy]phenyl]methyl]-​2,​4-​thiazolidinedione;​monopotassium salt

CAS号：316371-84-3

英文别名：5-​[[4-​[2-​(methyl-​2-​pyridinylamino)ethoxy]phenyl]methyl]-​2,​4-​thiazolidinedione;​monopotassium salt

分子量：395.5

分子式：C₁₈H₁₈N₃O₃S•K

纯度：>98%

外观：见爱必信官网

保存方法：Store at -20° C

描述：Rosiglitazone (potassium salt) is a PPARγ (peroxisome proliferator-activated subtype gamma receptor) agonist which regulates the epithelial sodium channel (ENaC) and Na-K-2Cl (NKCC2) co-transporter. Studies have shown that NKCC2 is inhibited by down regulation of the genes that code for the protein. Further studies have shown that Rosiglitazone increases the abundance of the α subunit of ENaC but causes a decrease in the abundance of cortical β- and γ-ENaC.

应用：A potent and selective PPARγ ligand

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