序号 | 名称 | CAS | 化学名称 | 结构式 |
1 | 莫西沙星EP杂质A | 151213-15-9 | 1-cyclopropyl-6,8-difluoro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
2 | 莫西沙星EP杂质B | 1029364-73-5 | 1-Cyclopropyl-1,4-dihydro-6,8-dimethoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid |
3 | 莫西沙星EP杂质C | 1029364-75-7 | 1-Cyclopropyl-8-ethoxy-6-fluoro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
4 | 莫西沙星EP杂质D | 1029364-77-9 | 1-Cyclopropyl-8-fluoro-1,4-dihydro-6-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid |
5 | 莫西沙星EP杂质E | 721970-36-1 | 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-hydroxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid |
6 | 莫西沙星杂质F | 721970-37-2 | 1-cyclopropyl-6-fluoro-8-methoxy-7-((4aS,7aS)-1-methylhexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
7 | 莫西沙星杂质G | 112811-71-9 | ethyl 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate |
8 | 莫西沙星杂质I | 139693-52-0 | 2,2-diacetoxy-6-cyclopropyl-8,9-difluoro-7-methoxy-4-oxo-4,6-dihydro-2H-[1,3,2]dioxaborinino[5,4-c]quinolin-1-ium-2-uide |
9 | 莫西沙星杂质J | 112811-72-0 | 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
10 | 莫西沙星杂质L | 172426-88-9 | 7-amino-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
11 | 莫西沙星杂质M | N/A | 1-cyclopropyl-6-fluoro-8-methoxy-7-((4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
12 | 莫西沙星杂质N | N/A | 7,7'-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridine-1,6(2H)-diyl)bis(1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid) |
13 | 莫西沙星杂质O | N/A | ethyl 1-cyclopropyl-7-fluoro-6,8-dimethoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate |
14 | 莫西沙星杂质P | 94242-51-0 | ethyl 1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate |
15 | 莫西沙星杂质Q | 1329836-33-0 | ethyl 1-cyclopropyl-7,8-difluoro-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate |
16 | 莫西沙星杂质R | 452092-31-8 | ethyl 1-cyclopropyl-6,7-difluoro-8-hydroxy-4-oxo-1,4-dihydroquinoline-3-carboxylate |
17 | 莫西沙星杂质S | NA | 1-cyclopropyl-7-fluoro-6-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride |
18 | 莫西沙星杂质T | 1797982-51-4 | 1-cyclopropyl-7-ethoxy-6-fluoro-8- methoxy-4-oxo-1,4-dihydroquinoline-3- carboxylic acid |
19 | 莫西沙星杂质U | NA | ethyl 1-cyclopropyl-8-ethoxy-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate |
20 | 莫西沙星杂质X | NA | 1-cyclopropyl-7-fluoro-6,8-dimethoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
21 | 莫西沙星杂质Y | NA | ethyl 1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-8-hydroxy-4-oxo-1,4-dihydroquinoline-3-carboxylate |
22 | 莫西光学对映体 莫西沙星杂质RR | 268545-13-7 | 1-cyclopropyl-6-fluoro-7-((4aR,7aR)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride |
23 | 莫西沙星杂质-S01 | 151213-45-5 | (4aS,7aS)-1-methyloctahydro-1H-pyrrolo[3,4-b]pyridine hydrochloride |
24 | 莫西沙星杂质-S02 | 151213-42-2 | (4aR,7aR)-octahydro-1H-pyrrolo[3,4-b]pyridine |
25 | RR-异构体 | NA | (5E,6Z)-1-cyclopropyl-5-(2-fluoroethylidene)-6-(2-((4aR,7aR)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-1-methoxyethylidene)-4-oxo-1,4,5,6-tetrahydropyridine-3-carboxylic acid hydrochloride |
26 | 莫西沙星杂质1 | NA | 1-cyclopropyl-8-ethoxy-6-fluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride |
27 | 莫西沙星杂质2 | NA | 1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-8-hydroxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
28 | 莫西沙星杂质3 | NA | ethyl 1-cyclopropyl-8-ethoxy-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate |
29 | 莫西沙星杂质4 | NA | methyl 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate |
30 | 莫西沙星杂质5 | NA | 1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
31 | 莫西沙星杂质6 | N/A | 1-cyclopropyl-7-fluoro-8-methoxy-6- ((4aS,7aS)-octahydro-6H-pyrrolo[3,4- b]pyridin-6-yl)-4-oxo-1,4- dihydroquinoline-3-carboxylic acid |