鼠抗人 ARMET(MANF,ARP)/FITC 单克隆荧光抗体

ARMET (Arginine rich, mutated in early stage of tumors) is also called ARP(arginine-rich protein)or MANF (mesencephalic astrocyte-derived neurotrophic factor)。 The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract.