品名 | anti- Phospho-VEGF Receptor 2-Y1175 antibody |
货号 | FNab09964 |
规格 | Immunogen affinity purified |
纯度 | ≥95% as determined by SDS-PAGE |
宿主 | Rabbit |
亚型 | IgG |
存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
背景介绍 | KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas. |
免疫原 | A phospho specific peptide corresponding to residues surrounding Y1175 of human VEGF Receptor 2 |
别称 | CD309|Fetal liver kinase 1|FLK 1|FLK1|KDR|Kinase insert domain receptor|VEGF Receptor 2|VEGFR|VEGFR 2|VEGFR2 |
分子量 | 250 kDa |
Uniprot ID | P35968 |
适用种属 | Human, Mouse, Rat |
验证应用 | ELISA, WB, IHC |
建议稀释比例 | WB: 1:500 - 1:1000; IHC: 1:50 - 1:100 |
图片 | | Immunohistochemistry of paraffin-embedded human breast carcinoma tissue slide using FNab09964 at dilution of 1:50 |
| HUVE cells were subjected to SDS PAGE followed by western blot with FNab09964 at dilution of 1:600 |
注意事项 | Phospho-VEGF Receptor 2-Y1175 antibody|Phospho-VEGF Receptor 2-Y1175抗体仅供科研使用 |
产品链接 | https://www.fn-test.cn/product/FNab09964/ |