Recombinant Human Secreted Ly-6,uPAR domain-containing protein 2(SLURP2)

host_species:Yeast

purification:Greater than 90% as determined by SDS-PAGE.

other_names:Secreted LY6,PLAUR domain-containing protein 2Secreted Ly-6,uPAR-related protein 2

accession_no:P0DP57

calculated_mw:10 kDa

tag info:N-terminal 6xHis-tagged

Immunogen Description:Expression Region:23-97aa
Sequence Info:Full Length of Mature Protein

formulation:Tris-based buffer50% glycerol

storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

background:Binds and may modulate the functional properties of nicotinic and muscarinic acetylcholine receptors. May regulate keratinocytes proliferation, differentiation and apoptosis. In vitro moderately inhibits ACh-evoked currents of alpha-3:beta-2-containing nAChRs and strongly these of alpha-4:beta-2-containing nAChRs, modulates alpha-7-containing nAChRs, and inhibits nicotine-induced signaling probably implicating alpha-3:beta-4-containing nAChRs. Proposed to act on alpha-3:beta-2 and alpha-7 nAChRs in an orthosteric, and on mAChRs, such as CHRM1 and CHRM3, in an allosteric manner.

产品详细信息请点击：Recombinant Human Secreted Ly-6,uPAR domain-containing protein 2(SLURP2)