Recombinant Human Tryptophan--tRNA ligase, cytoplasmic(WARS)

host_species:Yeast

purification:Greater than 85% as determined by SDS-PAGE.

other_names:Interferon-induced protein 53

accession_no:P23381

calculated_mw:56.5 kDa

tag info:N-terminal 6xHis-tagged and C-terminal Myc-tagged

Immunogen Description:Expression Region:2-471aa
Sequence Info:Full Length

formulation:Tris-based buffer50% glycerol

storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

background:Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.

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