Anti-CD53 monoclonal antibody, clone OX-44

　This product recognises the CD55 antigen, a 70kD glycoprotein also known as Decay Accelerating Factor (DAF). Distributed on erythrocytes and other circulating blood cells and also on cells in non-haemopoietic tissue particularly epithelium and endothelium. Found specifically at the foetal-maternal interfaces in placenta.CD55 has reduced expression on individuals with paroxysmal nocturnal haemoglobinuria. This antibody has a functional binding affinity to erythrocytes of 8.7 x 107 M-1. The antigen is pronase and trypsin resistant and chymotrypsin sensitive. BRIC 216 recognises the consensus region 3 of the DAF molecule, which contains the functional site, and the antibody blocks the function of DAF. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul　http://www.creative-diagnostics.com/Anti-CD53-Mab-235042-144.htm