生长因子此类产品包括人、小鼠或大鼠的细胞外蛋白,多数情况下可启始或影响通过细胞表面受体传递的信号。下列产品包括人、小鼠和大鼠的白细胞介素、集落刺激因子、生长因子、干扰素、脂肪因子、BMP蛋白、FGFs、TNFs、可溶性受体、细胞外结合蛋白、非抑制型丝氨酸蛋白酶抑制剂及其他免疫调节蛋白等。
Peprotech因子Recombinant Human IL-11新品促销
产品编号:
200-11
别名:
AGIF (Adipogenesis inhibitory factor)
描述:
IL-11 is a multifunctional cytokine produced by stromal cells, such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues, including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines, and protects against gastromucosal injury. Recombinant Human IL-11 is a 19.3 kDa protein consisting of 179 amino acid residues.
氨基酸序列:
MPGPPPGPPR VSPDPRAELD STVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine T11 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
交叉反应:
Monkey, Mouse, Human
研究领域:
| 血管生成/ 心血管 | | 细胞凋亡 |
| 癌症 | | 免疫系统 |
| 炎症 | | 干细胞及分化 |
原产国:
USA