优势供应 Sigma 放线菌素D A4262 2mg价格
CAS号 50-76-0
Actinomycin D from Streptomyces sp., ≥95% (HPLC)
别名: 放线菌素 C1 放线菌素 IV 更生霉素
Biochem/physiol Actions
An antineoplastic antibiotic that inhibits cell proliferation by forming a stable complex with DNA and blocking the movement of RNA polymerase which interferes with DNA-dependent RNA synthesis. Induces apoptosis. Potent antitumor agent. For cell culture applications, actinomycin D is used as a selection agent and is used in banding techniques to differentiate between different regions of chromosomes.
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