北京重组人白介素13,Recombinant Human IL-13 报价_详细资料

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北京重组人白介素13,Recombinant Human IL-13 报价
Recombinant Human IL-13
Catalog Number:
200-13
Synonyms:
NC30 （Human）, P600 （Murine）
Description:
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, ａnd also by mast cells ａnd NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development ａnd indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes ａnd macrophages ａnd it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 ａnd IL-8. IL-13 has also been shown to enhance B cell proliferation ａnd to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human ａnd murine IL-13 is cross-species reactive. Recombinant human IL-13 is a 12.6 kDa protein consisting of 115 amino acid residues.
AA Sequence:
MSPGPVPPST ALRELIEELV NITQNQKAPL CNGSMVWSIN LTAGMYCAAL ESLINVSGCS AIEKTQRMLS GFCPHKVSAG QFSSLHVRDT KIEVAQFVKD LLLHLKKLFR EGRFN
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
Biological Activity:
The ED₅₀ as determined by the dose-dependent proliferation of TF-1 cells was ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶units/mg.

Cross Reactivity:
Mouse, Human, Bacteria, Leech, Monkey, Pig
Research Interests:

AIDS / HIV Cancer

Immune System Inflammation

Stem Cells & Differentiation Allergy

Country of Origin:
USA

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北京 重组人白介素13,Recombinant Human IL-13 报价

产品信息

北京重组人白介素13,Recombinant Human IL-13 报价