代理 Peprotech Recombinant Murine IL-10 报价北京杰辉生物对外承揽试验:免疫组化,荧光,Tunel,Elisa,WB,原位杂交,比色法,HE染色,特染,图像分析,欢迎咨询!北京杰辉生物免费代测ELISA试剂盒一周内出结果
代理 Peprotech Recombinant Murine IL-10 报价
Catalog Number:
210-10
Synonyms:
B-TCGF, CSIF, TGIF
Description:
IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNFα. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 active on murine cells, but murine IL-10 is inactive on human cells. Recombinant murine IL-10 is an 18.7 kDa protein of 161 amino acid residues.
AA Sequence:
MSRGQYSRED NNCTHFPVGQ SHMLLELRTA FSQVKTFFQT KDQLDNILLT DSLMQDFKGY LGCQALSEMI QFYLVEVMPQ AEKHGPEIKE HLNSLGQKLK TLRMRLRRCH RFLPCENKSK AVEQVKSDFN KLEDQGVYKA MNEFDIFINC IEAYMMIKMK S
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
PeproTech's murine IL-10 is fully biologically active as measured by the dose-dependent co-stimulation (with IL-4) of the proliferation of murine MC/9 cells. The ED50 was found to be < 2 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg.
Cross Reactivity:
Human, Mouse, Rat
Research Interests:
 | AIDS / HIV |  | Cancer |
 | Immune System |  | Inflammation |
 | Neurobiology |  | Stem Cells & Differentiation |
 | Allergy |  | Transplantation |
Country of Origin:
USA