代理美国Peprotech Recombinant Murine IL-1β_详细资料

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代理美国Peprotech Recombinant Murine IL-1β
Recombinant Murine IL-1β
Catalog Number:
211-11B
Synonyms:
Catabolin, Lymphocyte-activating factor （LAF）, Endogenous Pyrogen （EP）, Leukocyte Endogenous Mediator （LEM）, Mononuclear Cell Factor （MCF）
Description:
IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes ａnd other epithelial cells. Both IL-1α ａnd IL-1β binds to the same receptor ａnd has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation ａnd proliferation, mitogenic FGF-like activity ａnd the ability to stimulate the release of prostaglandin ａnd collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant murine IL-1β is a 17.5 kDa protein containing 153 amino acid residues.
AA Sequence:
MVPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSS
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
Biological Activity:
The ED₅₀ as determined by the dose-dependent stimulation of murine D10S cells is ≤ 0.002 ng/ml, corresponding to a specific activity of ≥ 5 x 10⁸units/mg.

Cross Reactivity:
Human, Monkey, Pig, Rat, Mouse + Chicken, Mouse, Mouse + Bacteria, Human + Mouse
Research Interests:

Angiogenesis/ Cardiovascular Cancer

Diabetes / Weight Regulation Immune System

Inflammation Neurobiology

Proliferation Stem Cells & Differentiation

Wound Healing Allergy

Transplantation

Country of Origin:
USA

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代理美国Peprotech Recombinant Murine IL-1β

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	Angiogenesis/ Cardiovascular		Cancer
	Diabetes / Weight Regulation		Immune System
	Inflammation		Neurobiology
	Proliferation		Stem Cells & Differentiation
	Wound Healing		Allergy
	Transplantation

代理 美国Peprotech Recombinant Murine IL-1β

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代理美国Peprotech Recombinant Murine IL-1β