【产品介绍】Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two types of light chains designated as kappa and lambda (1). Light chain types are based on differences in the amino acid sequence in the constant region of the light chain. If a cell is unsuccessful in rearranging both of its kappa light chain genes, it then attempts to make a lambda light chain. If a cell successfully rearranges a lambda light chain gene, it will be a B cell that makes an immunoglobulin with a lambda light chain (2). Human Lambda light chain,Human Lambda Recommended Applications WB, IHC, ICC, IP, ELISA Applications and Recommended Dilution Factors WB: 1:50,000 - 200,000 IHC: 1:250 - 500 ICC: 1:500 - 1000 IP: 1:100 - 500 ELISA: 1:64,000 Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data Human Lambda light chain,Human Lambda Western blot analysis on (A) human tonsil, (B) human plasma, and (C) human spleen lysates using anti-Human Lambda light chain RabMAb (cat. #5185-1). Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Human Lambda light chain RabMAb (cat. #5185-1). Human Lambda light chain,Human Lambda Specificity A recombinant protein fragment corresponding to human IgA was used as an immunogen. |