FAK Antibody，Rabbit Monoclonal IgG_详细资料

产品信息

FAK Antibody，Rabbit Monoclonal IgG【反应特异性】Human , Mouse , Rat 【克隆 ID】EP695Y【用途】WB , IHC , ICC , IP【抗原分子量】125 kDa

FAK Antibody
Rabbit Monoclonal IgG

Cas 号：

分子式：

别名： FADK 1, pp125FAK, Protein-tyrosine kinase 2

订货信息：

货号品名规格包装单价货期订购

FAK Antibody 100ul 询价现货订购

性状：
【反应特异性】Human , Mouse , Rat
【克隆 ID】EP695Y
FAK Antibody，Rabbit Monoclonal IgG

【用途】WB , IHC , ICC , IP
【抗原分子量】125 kDa

质量标准： 【产品介绍】Focal adhesion kinase （FAK） is a non-recept
o r protein-tyrosine kinase implicated in signaling
pathways involved in cell motility, proliferation
a n d apoptosis （1）. FAK is composed of a central
catalytic domain flanked by large N- a n d
C-terminal regions. FAK is activated by phosph o r
ylation at tyrosine 397 in response to integrin
clustering which can be induced by cell adhesion
o r antibody cross-linking o r via G-protein-coupled
recept o r （GPCR） occupancy by lig a n d s such as
bombesin o r lysophosphatidic acid （2-3）. FAK expression
is upregulated in various tum o r s （4）. Increased
FAK expression has been c o r related with the
enhanced motility a n d invasiveness of human tum o r
cells, as well as with promoting increased
cell proliferation （5）.

FAK Antibody，Rabbit Monoclonal IgG
WB: 1:1,000
IHC: 1:50-100
ICC: 1:250-500
IP: 1:50

A. Western blot analysis on Hela cell lysate using
anti-FAK RabMAb （cat. # 1700-1）, dilution 1:1,000.

FAK Antibody，Rabbit Monoclonal IgG
B. Immunohistochemical analysis of paraffin-embedded
human hepatocellular carcinoma using anti-FAK RabMAb
（cat. # 1700-1）.

FAK Antibody，Rabbit Monoclonal IgG
C. Immunoflu o r escent staining of HeLa cells
using anti-FAK RabMAb （cat. # 1700-1）.

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FAK Antibody，Rabbit Monoclonal IgG

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货号	品名	规格	包装	单价	货期	订购
	FAK Antibody		100ul	询价	现货	订购