质量标准: | 【产品介绍】Erzin, a member of the Ezrin, Radixin, Moesin (ERM) family, is a linker protein located between cell surface recept o r s, adhesion molecules, a n d actin cytoskeleton (1-2). Ezrin activity is regulated by intramolecular interactions between N- a n d C-terminal ERM association domains (3). Phosph o r ylation at threonine 567 is a critical regulat o r of Ezrin function allowing the active protein to link target molecules to the actin cytoskeleton (4). Erzin tyrosine phosph o r ylation can also be induced by EGF, PDGF a n d HGF stimulation. Erzin interacts with PI3-K protein kinase A a n d Rho (5). Ezrin Phospho (pY353),Rabbit Monoclonal WB: 1:200,000 ICC: 1:100 - 250 Ezrin Phospho (pY353),Rabbit Monoclonal A. Western blot analysis on 293 cell lysates using anti-Phospho-Ezrin (pY353) RabMAb (cat. #1894-1), 1:200,000 dilution. Cells were either (A) untreated (B) treated with pervanadate. |