【产品介绍】Autophagy is a process of bulk degradation of cytoplasmic components by the lysosome/vacuole a n d has a significant relationship to several neurodegenerative dis o r ders a n d myopathies in mammals (1). Apg7 (Atg7) is a unique E1 enzyme which is essential f o r both the Apg12p- a n d Apg8p-modification systems, a n d plays indispensable roles in autophagy (2). A new molecular pathway has been defined in which activation of the recept o r -interacting protein (a serine-threonine kinase) a n d Jun amino-terminal kinase induced cell death with the m o r phology of autophagy. Autophagic death required Atg7 a n d beclin 1 a n d was induced by caspase-8 inhibition (3). Atg7 Rabbit Antibody,Rabbit Monoclonal WB: 1:500,000 IHC: 1:100 250 ICC: 1:250 500 Flow Cytometry: 1:95 IP: 1:50 Atg7 Rabbit Antibody,Rabbit Monoclonal A. Western blot analysis on Jurkat cell lysate using anti-Atg7 RabMAb (cat. # 2054-1), dilution 1:500,000. Atg7 Rabbit Antibody,Rabbit Monoclonal B. Immunohistochemical analysis of paraffin-embedded human liver using anti-Atg7 RabMAb (cat. #2054-1). |