【产品介绍】CD34 (Cluster of differentiation 34) is a single-pass type I transmembrane glycoprotein which primary functions as a cell to cell adhesion factor. As an adhesion factor, CD34 is expressed during stem/progenitor stage of lymphohematopoietic development and possibly mediates the stem cell attachment to the bone marrow ECM or stromal cells. CD34 is considered to be ideal marker for identifying and quantifying hematopoietic progenitor stem cells. With interaction with CrkL, CD34 becomes a substrate for PKC and CD34 surface expression is associated with activation of PKC. *Mouse reactivity was determined by IHC on mouse tissues. CD34,Rabbit Monoclonal Antibody Recommended Applications WB, IHC, ICC, IP, FC Applications and Recommended Dilution Factors WB: 1:10,000 - 100,000 IHC: 1:500-1,000 ICC: 1: 100 - 250 IP: 1:40 FC: 1:60 Species Reactivity * CD34,Rabbit Monoclonal Antibody Human *Mouse cross reactivity tested by western blot and IHC Rat cross reactivity tested by western blot only Products Data A. Western blot analysis on TF-1 using anti-CD34 RabMAb (cat # 2150-1), 1:100,000. CD34,Rabbit Monoclonal Antibody B. Immunohistochemical staining of paraffin-embedded human angiosarcoma using anti-CD34 RabMAb (cat. #2150-1). Specificity A synthetic peptide corresponding to C-terminal of human CD34 was used as an immunogen |