MAPK1(mitogen-activated protein kinase 1) encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of
【中文名称】:促分裂原活化蛋白激酶3 (细胞外信号调节激酶1/2) 单克隆抗体
【英语名称】:P44/42 MAPK (ERK1/2) Monoclonal Antibody
【产品类型】:一抗
【供应商】:Abbkine
【产品货号】:ABM40226
【产品规格】:30u/100ul/200ul
【背景资料】:MAPK1(mitogen-activated protein kinase 1) encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for MAPK1.蛋白别名为:MAPK3; ERK1; PRKM3; Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p;基因ID为:5594/5595;蛋白质ID:P27361/P28482
【应用类型】:WB,IHC-p补充:的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:1000-2000, IHC-p: 1:50-100.
【免疫原】:合成多肽
【来源宿主】:小鼠
【反应性】:人,小鼠,大鼠
【保存建议】:厂家推荐蓝冰运输.在发货后能在-20℃保存1年.为限度的避免损失,请在打开管盖之前融化抗体并离心.我们建议使用前分装以避免反复冻融.本产品为液体形式,溶解于PBS缓冲液中,含50%甘油,0.5%BSA和0.02%叠氮化钠.
【产品说明】:点击:促分裂原活化蛋白激酶3 (细胞外信号调节激酶1/2) 单克隆抗体查看更详细产品说明,更多应用、储存、价格、货期等信息请致电垂询AbbkineZG区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看每日生物评论网站。
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