CASP1 (caspase 1)encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. CASP1 was identified by its ability to proteolytically cleave and activate the inactive precursor of inter
艾美捷科技有限公司,目前提供Abbkine高质量抗体:Caspase-1 多克隆抗体,性价比非常高。Abbkine致力于为生命科学研究和YL发展提供的产品和技术。Abbkine设计、开发、生产并销售了一系列独特的产品,包括生命科学领域研究相关的抗体、研究试剂以及细胞功能分析产品。Abbkine的产品为科学研究中的挑战提供卓有成效的解决方案,从而为的科学家节省时间并提高研究效率。作为Abbkine的ZG区域总代理,艾美捷科技有限公司凭借丰富的专业经验,将一如既往的为ZG区域客户提供Abbkine优质的产品和技术服务。
【英文名称】:Caspase-1 Polyclonal Antibody
【中文名称】:Caspase-1 多克隆抗体
【产品类型】:一抗
【供应商】:Abbkine
【产品货号】:ABP57468
【背景资料】:CASP1 (caspase 1)encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. CASP1 was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. CASP1 has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.蛋白别名为:caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase);基因ID为:834;蛋白质ID:P29466
【产品规格】:30u/100ul/200ul
【应用类型】:WB,ELISA补充:的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-2000, ELISA 1:10000-20000.
【免疫原】:合成多肽:Caspase-1 . at AA range: internal
【来源宿主】:兔
【反应性】:人,大鼠
【保存建议】:厂家推荐蓝冰运输.在发货后能在-20℃保存1年.为限度的避免损失,请在打开管盖之前融化抗体并离心.我们建议使用前分装以避免反复冻融.本产品为液体形式,溶解于PBS缓冲液中,含50%甘油,0.5%BSA和0.02%叠氮化钠.
【产品说明】:点击:Caspase-1 多克隆抗体查看更详细产品说明,更多应用、储存、价格、货期等信息请致电垂询AbbkineZG区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看每日生物评论网站。
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