产品编号Rs-9294R 英文名称BTBD1 中文名称BTB/POZ结构域蛋白1(丙型肝炎病毒的NS反转录蛋白8)抗体 别 名BTB (POZ) domain containing 1; BTB domain containing 1; BTB/POZ domain containing protein 1; BTBD 1; BTBD1; C15orf1; HCV NS transactivated protein 8; Hepatitis C virus NS transactivated protein 8; NSTP8; BTBD1_HUMAN. 说 明 书0.2ml 研究领域细胞生物 细胞周期蛋白 转录调节因子 细菌及病毒 细胞分化 抗体来源Rabbit 克隆类型Polyclonal 交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量53kDa 细胞定位细胞浆 性 状Lyophilized or Liquid 浓 度1mg/1ml 免 疫 原KLH conjugated synthetic peptide derived from human BTBD1 亚 型IgG 纯化方法affinity purified by Protein A 储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMedPubMed 产品介绍background: BTBD1 contains a proline-rich region and a BTB/POZ domain which are typically involved in protein-protein interactions. The C-terminus of BTBD1 binds topoisomerase I and BTBD1 also interacts with TRIM5 isoform Delta. BTBD1 localizes to cytoplasmic bodies and is essential for myogenic differentiation.
Function: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Subunit: Interacts with topoisomerase 1 and with TRIM5 isoform Delta. Interacts with CUL3.