肿瘤/睾丸抗原2.2/睾丸抗原2.3抗体_详细资料

产品信息 肿瘤/睾丸抗原2.2/睾丸抗原2.3抗体，应用于IHC、WB、 IF、IP、ELISA等实验，公司生产的抗体每个流程都执行严格的检测标准，保证蛋白抗原产品质量，质量稳定，实验效果明显。按理化性质和生物学功能，可将其分为IgM、IgG、IgA、IgE、IgD五类。公司产品经无数次市场验证，若出 产品编号Rs-9114R 英文名称BAGE2 + BAGE3 中文名称肿瘤/睾丸抗原2.2/睾丸抗原2.3抗体 别名B melanoma antigen 2; B melanoma antigen family, member 2; Cancer/testis antigen 2.2; CT2.2; BAGE2_HUMAN; B melanoma antigen family member 3; B melanoma antigen 3; BAGE3; BAGE3_HUMAN; Cancer/testis antigen 2.3; Cancer/testis antigen family 2 member 3; CT2.3. 说明书0.2ml 研究领域肿瘤细胞生物免疫学 抗体来源Rabbit 克隆类型Polyclonal 交叉反应Human, 产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量10kDa 细胞定位分泌型蛋白 性状Lyophilized or Liquid 浓度1mg/1ml 免疫原KLH conjugated synthetic peptide derived from human BAGE2 ａnd BAGE2 亚型IgG 纯化方法affinity purified by Protein A 储存液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 ａnd 50% Glycerol. 保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMedPubMed 产品介绍background: Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes ａnd are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 ａnd BAGE 3 (B melanoma antigen 2 ａnd 3, respectively), also known as Cancer/testis antigen 2.2 ａnd 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung ａnd bladder carcinomas, ａnd are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis. Function: Unknown. Candidate gene encoding tumor antigens. Subcellular Location: Secreted. Tissue Specificity: Not expressed in normal tissues except in testis. Expressed in 22% of melanomas, in bladder ａnd lung carcinomas. Similarity: Belongs to the BAGE family. Gene ID: 85319 Database links: Entrez Gene: 85319 Human SwissProt: Q86Y30 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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