Anti-TP/thymidine phosphorylase胸苷磷酸化酶抗体

本公司经销TP/thymidine phosphorylase，胸苷磷酸化酶抗体，克隆类型为polyclonal，宿主来源是Rabbit，TP/thymidine phosphorylase胸苷磷酸化酶抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-3809R
英文名称：Anti-TP/thymidine phosphorylase
中文名称：胸苷磷酸化酶抗体
其他名称：名ECGF 1; PDEGF; ECGF1; Endothelial cell growth factor 1; Endothelial cell growth factor 1 platelet derived; Gliostatin; hPD ECGF; MNGIE; PD ECGF; PDECGF; PDEGF; Platelet derived endothelial growth factor; TdRPase; TP; TYMP; Thymidine Phosphorylase; TYPH_HUMAN; TdRPase.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 50kDa
纯化方法：affinity purified by Protein A
交叉反应：hu
产品介绍：In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor （PD-ECGF） thymidine phosphorylase （TP） （gliostatin） catalyses the reversible phospholytic cleavage of thymidine ａnd deoxyuridine to their corresponding bases ａnd 2-deoxyribose-1-phosphate. It is both chemotactic ａnd mitogenic for endothelial cells ａnd a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.Subunit : Homodimer.Similarity : Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.胸苷磷酸化酶（TP）是一种分子量为50-55kDa的蛋白，在氟嘧啶转化过程中起重要作用。TP具有血管生成活性，与血小板源性内皮细胞生长因子的结构和作用相似，因此又被称为肿瘤相关血管生长因子。其可能通过血管生成作用促进癌细胞的生长和转移。