本公司经销NGB/neuroglobin,脑红蛋白/神经血红蛋白/神经球蛋白抗体,克隆类型为polyclonal,宿主来源是Rabbit,NGB/neuroglobin脑红蛋白/神经血红蛋白/神经球蛋白抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
本公司经销NGB/neuroglobin,脑红蛋白/神经血红蛋白/神经球蛋白抗体,克隆类型为polyclonal,宿主来源是Rabbit,NGB/neuroglobin脑红蛋白/神经血红蛋白/神经球蛋白抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
货号:BY-1859R
英文名称:Anti-NGB/neuroglobin
中文名称:脑红蛋白/神经血红蛋白/神经球蛋白抗体
其他名称:名neuroglobin; NGB.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 17kDa
纯化方法:affinity purified by Protein A
交叉反应:mo, rat, hu, Rb, cow, pig
产品介绍:Neuroglobin, a 151 amino acid reside protein, mainly expressed in vertebrate brain and retina, is a recently identified member of the globin superfamily. Augmenting O2 supply, neuroglobin promotes survival of neurons upon hypoxic injury, potentially limiting brain damage. Moreover, neuroglobin may be a novel oxidative stress-responsive sensor for signal transduction in the brain. Neuroglobin expression is increased by neuronal hypoxia in vitro and focal cerebral ischemia in vivo, and neuronal survival after hypoxia is reduced by inhibiting neuroglobin expression with an antisense oligodeoxynucleotide and enhanced by neuroglobin overexpression.Subunit : Monomer. Homodimer and homotetramer; disulfide-linked (By similarity).Subcellular Location : Perikaryon (By similarity).Tissue Specificity : Predominantly expressed in brain, the strongest expression is seen in the frontal lobe, the subthalamic nucleus and the thalamus.Similarity : Belongs to the globin family.Neuroglobin是一种在神经组织和神经冲动中携氧、转运氧气和供氧的特异性蛋白,并和神经组织微循环有关,神经球蛋白能在缺氧的环境下保护神经元.