Anti-Nucleoprotein/NPA型流感病毒核蛋白抗体

本公司经销Nucleoprotein/NP，A型流感病毒核蛋白抗体，克隆类型为polyclonal，宿主来源是Rabbit，Nucleoprotein/NPA型流感病毒核蛋白抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-4976R
英文名称：Anti-Nucleoprotein/NP
中文名称：A型流感病毒核蛋白抗体
其他名称：名Nucleoprotein; Nucleocapsid protein; Protein N; Influenza A virus H1N1, H3N2, H9N2, H2N2, H3N8, H7N7, H5N1.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 56kDa
纯化方法：affinity purified by Protein A
交叉反应：Influenza A virus
产品介绍：Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein （RNP） ａnd serves as template for transcription ａnd replication. The RNP needs to be localized in the nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals ａnd is responsible of the active RNP import into the nucleus through the cellular importin alpha/beta pathway. Later in the infection, nucleus export of RNP are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that the nucleoprotein binds directly exportin-1 （XPO1） ａnd plays an active role in RNP nuclear export. M1 interaction with RNP seems to hide nucleoprotein＇s nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmask nucleoprotein＇s nuclear localization signals, targeting the RNP to the nucleus.Subcellular Location : Virion. Host nucleus