本公司经销NIS,钠碘转运体蛋白抗体,克隆类型为polyclonal,宿主来源是Rabbit,NIS钠碘转运体蛋白抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
本公司经销NIS,钠碘转运体蛋白抗体,克隆类型为polyclonal,宿主来源是Rabbit,NIS钠碘转运体蛋白抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
货号:BY-0448R
英文名称:Anti-NIS
中文名称:钠碘转运体蛋白抗体
其他名称:名Na(+)/I(-) cotransporter; Na(+)/I(-) symporter; Na(+)/I(-) cotransporter; Na(+)/I(-) symporter; Na+/I- cotransporter; Na+/I-symporter; NIS; SC5_HUMAN; SLC5; sodium iodide symporter; Sodium-iodide symporter; Sodium/iodide cotransporter; Solute carrier family 5 (sodium iodide symporter) member 5; Solute carrier family 5; Solute carrier family 5 member 5.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 65kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
产品介绍:catalyzes Na+/I- symporter activity plays a role in iodide transport and thyroid hormone generation.Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid.钠/碘转运体蛋白-NIS,是位于甲状腺细胞基底膜上的一类膜抗原,在甲状腺对碘的主动转运过程中发挥重要作用。 钠/碘转运蛋白受甲状腺刺激素(TSH)、碘、细胞因子和生长因子等多种因素的广泛调节。自身免疫性甲状腺疾病时NIS的表达发生了明显变化,患者体内出现抗NIS自身抗体。 此外,NIS还与甲状腺冷结节和先天性甲状腺机能减退等甲状腺疾病的发病机理密切相关,近年来得到了足够的重视。产品图片Tissue/cell: rat thyroid gland; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-NIS Polyclonal Antibody, Unconjugated(bs-0448R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) stainingTissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-NIS Polyclonal Antibody, Unconjugated(bs-0448R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining