DNA连接酶4抗体,Anti-DNA Ligase IV/LIG4抗体

博研生物抗体售前、售中、售后免费技术服务，欢迎致电索说明书

客服电话：021 60340850    021 60340830    021 60340820
客服QQ ：827774711    349199432     372584443 
产品名称  DNA连接酶4抗体,Anti-DNA Ligase IV/LIG4抗体                                             
产品编号 BYk-1677R    

相关标记 HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-Cy5 PE-Cy5.5
PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
浓 度 1mg/1ml
抗体来源 Rabbit OR MOUSE
克隆类型 polyclonal or monoclonal
产品类型 一抗
产品用途  科研实验，用于免疫组化实验，WB实验、IF、IP、ELISA实验，相应的标记抗体有HRP标记抗体，FITC标记，BIO等。
性 状 Lyophilized or Liquid
亚 型 IgG     

DNA连接酶4抗体,Anti-DNA Ligase IV/LIG4抗体保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

DNA连接酶4抗体,Anti-DNA Ligase IV/LIG4抗体产品说明：

The X-ray repair cross-complementing protein XRCC4 ａnd DNA Ligase IV are essential for repairing double-strand breaks in DNA. These proteins form a critical complex consisting of two molecules of each protein that preferentially bind DNA with nicks or broken ends. As an obligate accessory molecule, XRCC4 binds to DNA Ligase IV ａnd enhances its joining activity. The XRCC4/ DNA Ligase IV complex is also involved in V（D）J recombination. V（D）J recombination occurs in normal development of the adaptive immune system ａnd involves the formation of a double-strand break intermediate. Deletions of either DNA Ligase IV or XRCC4 inhibit the completion of V（D）J recombination, resulting in a high incidence of apoptosis in the developing nervous system ａnd a block in B ａnd T cell maturation.