“诱捕受体2抗体,Anti-DcR2/CD264/TNFRSF10D抗体”我公司拥有领先的细胞服务技术，先进的仪器设备和专业的ELISA检测试剂盒、生物索标记、荧光索标记、酶标记等，广泛用于多种分析研究与技术测定。欢迎来电咨询，我们将竭诚为你服务！
博研生物抗体售前、售中、售后免费技术服务，欢迎致电索说明书
客服电话：021 60340850 021 60340830 021 60340820
客服QQ ：827774711 349199432 372584443
产品名称 诱捕受体2抗体,Anti-DcR2/CD264/TNFRSF10D抗体
产品编号 BYk-1694R
相关标记 HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-Cy5 PE-Cy5.5
PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
浓 度 1mg/1ml
抗体来源 Rabbit OR MOUSE
克隆类型 polyclonal or monoclonal
产品类型 一抗
产品用途 科研实验，用于免疫组化实验，WB实验、IF、IP、ELISA实验，相应的标记抗体有HRP标记抗体，FITC标记，BIO等。
性 状 Lyophilized or Liquid
亚 型 IgG
诱捕受体2抗体,Anti-DcR2/CD264/TNFRSF10D抗体保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
诱捕受体2抗体,Anti-DcR2/CD264/TNFRSF10D抗体产品说明：
Apoptosis is induced by certain cytokines including TNF ａnd Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L, a member of the TNF family, induces apoptosis of a variety of tumor cell lines. DR4 ａnd DR5 are functional receptors for TRAIL, ａnd DcR1/TRID is a decoy receptor. Another member of the TRAIL receptor family was identified ａnd designated DcR2. The DcR2 receptor is 386 amino acids in length ａnd has an extracellular TRAIL binding domain, but lacks intracellular death domain ａnd does not induce apoptosis. Although this receptor binds to the cytotoxic ligand TRAIL, it contains a truncated death domain ａnd functions as an inhibitory receptor. When overexpressed, the DcR2 receptor can protect cells against TRAIL mediated cytotoxicity. Like DR4 ａnd DR5, DcR2 transcript is widely expressed in a variety of normal human tissues but DcR2 is absent in most tumors. Ultraviolet radiation has been shown to upregulate DcR2 expression on human keratinocytes. Over expression of DcR2 attenuated TRAIL induced apoptosis.
