多巴胺转运蛋白DAT抗体,Anti-DAT/Dopamine transporter抗体

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产品名称  多巴胺转运蛋白DAT抗体,Anti-DAT/Dopamine transporter抗体                                             
产品编号 BYk-1714R    

相关标记 HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-Cy5 PE-Cy5.5
PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
浓 度 1mg/1ml
抗体来源 Rabbit OR MOUSE
克隆类型 polyclonal or monoclonal
产品类型 一抗
产品用途  科研实验，用于免疫组化实验，WB实验、IF、IP、ELISA实验，相应的标记抗体有HRP标记抗体，FITC标记，BIO等。
性 状 Lyophilized or Liquid
亚 型 IgG     

多巴胺转运蛋白DAT抗体,Anti-DAT/Dopamine transporter抗体保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

多巴胺转运蛋白DAT抗体,Anti-DAT/Dopamine transporter抗体产品说明：

Plasmalemmal neurotransmitter transporters sequester synaptic ａnd peri synaptic transmitter into presynaptic elements. The Dopamine Transporter （DAT） is responsible for the reaccumulation of dopamine after it has been released. Levels of DAT protein expression are altered by chronic drug administration. The activity of the DAT reuptake carrier is sodium dependent, ａnd it is suspected to play a role in such neurologic ａnd psychiatric disorders as Parkinson＇s disease, Tourette＇s disease, schizophrenia, ａnd addiction. It is a 12 transmembrane domain transporter with the N ａnd C terminal regions located within the cytoplasm. Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
Involvement in disease:
Defects in SLC6A3 are the cause of dystonia-parkinsonism infantile （DYTPRI） . It is a neurodegenerative disorder characterized by infantile onset of parkinsonism ａnd dystonia. Other neurologic features include global developmental delay, bradikinesia ａnd pyramidal tract signs.