磷酸化CREB-1抗体,Anti-phospho-CREB-1(Ser133)抗体

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产品名称  磷酸化CREB-1抗体,Anti-phospho-CREB-1（Ser133）抗体                                             
产品编号 BYk-0036R    

相关标记 HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-Cy5 PE-Cy5.5
PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
浓 度 1mg/1ml
抗体来源 Rabbit OR MOUSE
克隆类型 polyclonal or monoclonal
产品类型 一抗
产品用途  科研实验，用于免疫组化实验，WB实验、IF、IP、ELISA实验，相应的标记抗体有HRP标记抗体，FITC标记，BIO等。
性 状 Lyophilized or Liquid
亚 型 IgG     

磷酸化CREB-1抗体,Anti-phospho-CREB-1（Ser133）抗体保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

磷酸化CREB-1抗体,Anti-phospho-CREB-1（Ser133）抗体产品说明：

The ATF/CREB family consists of transcription factors that function through binding to the cAMP responsive element （CRE） palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2, ATF-1,ATF-2,ATF-3and ATF-4. these transcription factors share highly-related COOH terminal leucine zipper demerization ａnd basic DNA bindings but are highly divergent in their amino terminal domains. Although each of the ATF/CREB proteins bind CREs in their homodimeric form, in cerain instances they also bind as heterodimers, both within the ATF/CREB family ａnd with members of the AP-1 transcription factor family. It has recentlybeen shown that protein kinase A-mediated CREB phosphorylation results in its binding to a 265kDa nuclear protein designated CBP （CREB-binding protein）, which may reprecent a CREB co-activator.