本公司经销phospho-KLF5(Ser275),磷酸化KLF5抗体,克隆类型为polyclonal,宿主来源是Rabbit,phospho-KLF5(Ser275)磷酸化KLF5抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
本公司经销phospho-KLF5(Ser275),磷酸化KLF5抗体,克隆类型为polyclonal,宿主来源是Rabbit,phospho-KLF5(Ser275)磷酸化KLF5抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
货号:BY-2020R
英文名称:Anti-phospho-KLF5(Ser275)
中文名称:磷酸化KLF5抗体
其他名称:名Klf5; CKLF; Krueppel-like factor 5; Intestinal-enriched krueppel-like factor; Transcription factor BTEB2; Basic transcription element-binding protein 2; BTE-binding protein 2; Krueppel-like factor 5; KLF5; basic transcription element-binding protein 2;BTEB2; intestine enriched krüppel-like factor; IKLF; Kruppel like factor 5; Transcription factor BTEB 2; Transcription factor BTEB2.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 50kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, hrs, cow, Rb, pig, dog
产品介绍:Krüppel-like factors (KLFs) zinc finger-containing transcription factors with regulatory functions in cell growth, proliferation, differentiation, and embryogenesis. KLF5, (also known as BTEB2 and IKLF), is essential for mouse embryo development. KLF5 activates many genes during cardiovascular remodeling, including PDGFa/b, Egr-1, PAI-1, iNOS, and VEGF receptors, making KLF a potential therapeutic target for cardiovascular disease. KLF5 also plays a role in angiogenesis and in development of several tumor types including breast, prostate, bladder, colon, esophagus, and skin. KLF5 is closely related to other of the KLF family members. However, KLF5 and KLF4 exhibit opposite effects on regulation of gene transcription, despite binding to similar, if not identical, cis-acting DNA sequences. In addition, KLF4 and 5 exert contrasting effects on cell proliferation in many instances; while KLF4 is an inhibitor of cell growth, KLF5 stimulates proliferation. KLF5 protein is enriched in intestinal tissue.