LALBA/alpha Lactalbumin乳清蛋白α抗体

本公司经销LALBA/alpha Lactalbumin，乳清蛋白α抗体，克隆类型为polyclonal，宿主来源是Rabbit，LALBA/alpha Lactalbumin乳清蛋白α抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-11131R
英文名称：Anti-LALBA/alpha Lactalbumin
中文名称：乳清蛋白α抗体
其他名称：名a-LACTA; alfaLA; Alpha-lactalbumin; Lactalbumin alpha; Lactose synthase B protein; LALBA; LALBA_HUMAN; Lysozyme-like protein 7; LYZL7.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 14kDa
纯化方法：affinity purified by Protein A
交叉反应：hu
产品介绍：Alpha-lactalbumin is the B protein of lactose synthetase secreted by the mammary epithelial cells. It is a potent Ca2+-elevating ａnd apoptosis-inducing agent with broad, yet selective, cytotoxic activity. Multimeric ?lactalbumin has been shown to kill all transformed, embryonic ａnd lymphoid cells tested, but not mature epithelial elements. This suggests that milk contributes to mucosal immunity not only by furnishing antimicrobial molecules but also by policing the function of lymphocytes ａnd epithelium. ?lactalbumin may be helpful in discovering the site of origin of metastatic breast tumors. Human lactalbumin contains 123 amino acid residues. Comparison of the 5＇ flanking sequences of the two Alpha-lactalbumin genes with those of five casein genes reveals the presence of a highly conserved region extending from position -140 to -110 in all seven sequences examined, suggesting a possible regulatory role in the hormonal control or tissue-specific expression of milk protein genes in the mammary gland.Function : Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.Subunit : Lactose synthase （LS） is a heterodimer of a catalytic component, beta1,4-galactosyltransferase （beta4Gal-T1） ａnd a regulatory component, alpha-lactalbumin （LA）.Subcellular Location : Secreted.Tissue Specificity : Mammary gland specific. Secreted in milk.Similarity : Belongs to the glycosyl hydrolase 22 family.