Mafav-maf 肌腱膜纤维肉瘤癌基因同源物A抗体

本公司经销Mafa，v-maf 肌腱膜纤维肉瘤癌基因同源物A抗体，克隆类型为polyclonal，宿主来源是Rabbit，Mafav-maf 肌腱膜纤维肉瘤癌基因同源物A抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-0924R
英文名称：Anti-Mafa
中文名称：v-maf 肌腱膜纤维肉瘤癌基因同源物A抗体
其他名称：名Mafa homolog; V-maf musculoaponeurotic fibrosarcoma oncogene homolog A;Pancreatic beta-cell-specific transcriptional activator;（avian）（V-maf musculoaponeurotic fibrosarcoma oncogene homolog A.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 37kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：Insulin gene expression is regulated by several islet-enriched transcription factors. However, MAFA is the only beta cell-specific activator. MAFA selectively induces endogenous insulin transcription in non-beta cells. MAFA was also first detected in the insulin-producing cells formed during the second ａnd predominant phase of beta cell differentiation, ａnd absent in the few insulin-positive cells found in Nkx6.1（-/-） pancreata, which lack the majority of second-phase beta cells. These results demonstrate that MAFA is a potent insulin activator that is likely to function downstream of Nkx6.1 during islet insulin-producing cell development.