SLC2A4RG/GLUT4 enhancer factor葡萄糖转运蛋白4增强因子抗体

本公司经销SLC2A4RG/GLUT4 enhancer factor，葡萄糖转运蛋白4增强因子抗体，克隆类型为polyclonal，宿主来源是Rabbit，SLC2A4RG/GLUT4 enhancer factor葡萄糖转运蛋白4增强因子抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-9457R
英文名称：Anti-SLC2A4RG/GLUT4 enhancer factor
中文名称：葡萄糖转运蛋白4增强因子抗体
其他名称：名GEF;GLUT4 enhancer factor;HDBP 1;HDBP-1;HDBP1;Huntington disease gene regulatory region binding protein 1;Huntington disease gene regulatory region-binding protein 1;S2A4R_HUMAN;Si 1 2 19;Si 1 2;SLC2A4 regulator;SLC2A4RG;Zinc finger protein 2 5 Glut4 enhancer factor.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 41kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo
产品介绍：SLC2A4RG （SLC2A4 regulator）, also known as Huntington disease gene regulatory region-binding protein 1 ａnd GLUT4 enhancer factor, is a 387 amino acid transcription factor that is involved in Glut4 ａnd HD gene transactivation. In cooperation with MEF-2, SLC2A4RG binds to domain I of the Glut4 promoter to regulate transcription of Glut4. Interestingly, after a single bout of exercise, there is an increase in DNA binding activities of both SLC2A4RG ａnd MEF-2, which leads to an increase in transcription of Glut4. This is significant because overexpression of Glut4 in skeletal muscle has shown to improve glucose homeostasis ａnd enhance insulin action. Also, by recognizing the 5’-GCCGGCG-3’ DNA sequence motif of the Huntington’s disease （HD） promoter, SLC2A4RG regulates transcription of the HD gene. Ubiquitously expressed with highest expression in skeletal muscle, liver, kidney, heart ａnd pancreas, SLC2A4RG shuttles between the cytoplasm ａnd nucleus ａnd contains a C2H2-type zinc finger that is involved in DNA binding. There are two isoforms of SLCA4RG that are produced as a result of alternative splicing.