本公司经销VRK1,牛痘病毒相关激酶1抗体(丝氨酸/苏氨酸蛋白激酶VRK1),克隆类型为polyclonal,宿主来源是Rabbit,VRK1牛痘病毒相关激酶1抗体(丝氨酸/苏氨酸蛋白激酶VRK1)可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
本公司经销VRK1,牛痘病毒相关激酶1抗体(丝氨酸/苏氨酸蛋白激酶VRK1),克隆类型为polyclonal,宿主来源是Rabbit,VRK1牛痘病毒相关激酶1抗体(丝氨酸/苏氨酸蛋白激酶VRK1)可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
货号:BY-7706R
英文名称:Anti-VRK1
中文名称:牛痘病毒相关激酶1抗体(丝氨酸/苏氨酸蛋白激酶VRK1)
其他名称:名PCH1;Serine/threonine protein kinase VRK1;Serine/threonine-protein kinase VRK1;Vaccinia related kinase 1;Vaccinia virus B1R related kinase 1;Vaccinia-related kinase 1;VRK1;VRK1_HUMAN;MGC117401;MGC138280;MGC142070
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 45kDa
纯化方法:affinity purified by Protein A
交叉反应:Human, Mouse
产品介绍:Serine/threonine kinase that phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2.Tissue specificity:Widely expressed. Highly expressed in fetal liver, testis and thymus.Involvement in disease: Defects in VRK1 are the cause of pontocerebellar hypoplasia type 1 (PCH1) ; also called pontocerebellar hypoplasia with infantile spinal muscular atrophy or pontocerebellar hypoplasia with anterior horn cell disease. PCH1 is characterized by an abnormally small cerebellum and brainstem, central and peripheral motor dysfunction from birth, gliosis and anterior horn cell degeneration resembling infantile spinal muscular atrophy (SMA).