TRIB3/p65 interacting inhibitor of NF-kappaB神经细胞死亡诱导蛋白激酶抗体

本公司经销TRIB3/p65 interacting inhibitor of NF-kappaB，神经细胞死亡诱导蛋白激酶抗体，克隆类型为polyclonal，宿主来源是Rabbit，TRIB3/p65 interacting inhibitor of NF-kappaB神经细胞死亡诱导蛋白激酶抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-7538R
英文名称：Anti-TRIB3/p65 interacting inhibitor of NF-kappaB
中文名称：神经细胞死亡诱导蛋白激酶抗体
其他名称：名C20orf97; Neuronal cell death inducible putative kinase; Neuronal cell death-inducible putative kinase; NIPK; p65 interacting inhibitor of NF-kappaB; p65-interacting inhibitor of NF-kappa-B; SINK; SKIP 3; SKIP3; TRB 3; TRB-3; TRB3; TRIB 3; Trib3; TRIB3_HUMAN; Tribbles homolog 3; Tribbles3.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 40kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, hrs, pig, chk, cow, dog, Rb
产品介绍：Disrupts insulin signaling by binding directly to Akt kinases ａnd blocking their activation. May bind directly to ａnd mask the ＇Thr-308＇ phosphorylation site in AKT1. Binds to ATF4 ａnd inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA ａnd inhibits its phosphorylation ａnd thus its transcriptional activation activity. Interacts with MAPK kinases ａnd regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity.Tissue specificity:Highest expression in liver, pancreas, peripheral blood leukocytes ａnd bone marrow. Also highly expressed in a number of primary lung, colon ａnd breast tumors. Expressed in spleen, thymus, ａnd prostate ａnd is undetectable in other examined tissues, including testis, ovary, small intestine, colon, leukocyte, heart, brain, placenta, lung, skeletal muscle, ａnd kidney.Subunit : Interacts with AKT1, AKT2, ATF4, MAP2K1 ａnd MAP2K7.Subcellular Location : Nucleus.Tissue Specificity : Highest expression in liver, pancreas, peripheral blood leukocytes ａnd bone marrow. Also highly expressed in a number of primary lung, colon ａnd breast tumors. Expressed in spleen, thymus, ａnd prostate ａnd is undetectable in other examined tissues, including testis, ovary, small intestine, colon, leukocyte, heart, brain, placenta, lung, skeletal muscle, ａnd kidney.Similarity : Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily.Contains 1 protein kinase domain.产品图片Antigen: bs-7538P, 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti-Rabbit IgG（bs-0295G-HRP） at 1: 5000; TMB（C-0024） staining; Read the data in MicroplateReader by 450nm.