本公司经销RNASE4/Angiogenin,血管生成素核糖核酸酶4抗体(肌萎缩性侧索硬化症蛋白),克隆类型为polyclonal,宿主来源是Rabbit,RNASE4/Angiogenin血管生成素核糖核酸酶4抗体(肌萎缩性侧索硬化症蛋白)可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
本公司经销RNASE4/Angiogenin,血管生成素核糖核酸酶4抗体(肌萎缩性侧索硬化症蛋白),克隆类型为polyclonal,宿主来源是Rabbit,RNASE4/Angiogenin血管生成素核糖核酸酶4抗体(肌萎缩性侧索硬化症蛋白)可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
货号:BY-6583R
英文名称:Anti-RNASE4/Angiogenin
中文名称:血管生成素核糖核酸酶4抗体(肌萎缩性侧索硬化症蛋白)
其他名称:名ALS9; AMYOTROPHIC LATERAL SCLEROSIS; ANG 1; ANG; ANG I; ANG1; ANGI; ANGI_HUMAN; Angiogenin; Angiogenin ribonuclease RNase A family, 5; Epididymis luminal protein 168; HEL168; MGC22466; MGC71966; Ribonuclease 5; Ribonuclease RNase A Family 5; RNase 5; RNASE4; RNASE5.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 13/16kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, hrs, pig
产品介绍:May function as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.Subcellular Location : Secreted.Tissue Specificity : Expressed predominantly in the liver. Also detected in endothelial cells and spinal cord neurons.Similarity : Belongs to the pancreatic ribonuclease family.Involvement in disease; Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9) . ALS is a degenerative disorder of motor neurons in the cortex, brain stem and spinal cord. ALS is characterized by muscular weakness and atrophy.