Piccolo神经细胞突触蛋白PCLO抗体

本公司经销Piccolo，神经细胞突触蛋白PCLO抗体，克隆类型为polyclonal，宿主来源是Rabbit，Piccolo神经细胞突触蛋白PCLO抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-11354R
英文名称：Anti-Piccolo
中文名称：神经细胞突触蛋白PCLO抗体
其他名称：名ACZ; Aczonin; Brain-derived HLMN protein; DKFZp779G1236; KIAA0559; Multidomain presynaptic cytomatrix protein; PCLO; PCLO_HUMAN; Piccolo （presynaptic cytomatrix protein）; Piccolo, mouse, homolog of antibody Pico; Presynaptic cytomatrix protein; Protein piccolo.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 557kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, cow, dog
产品介绍：Piccolo is 1 component of the presynaptic cytomatrix. Bassoon is a large protein which is also found in the presynaptic compartments of rat brain synapses. Bassoon, along with Piccolo, is part of the ensemble of presynaptic proteins that are involved in orchestrating events at the nerve terminal. Bassoon is found in axon terminals of hippocampal neurons where it is highly concentrated in the vicinity of the active zone. Piccolo has a similar distribution ａnd colocalizes with Bassoon in cultured hippocampal cells. Piccolo zinc fingers interact with the dual prenylated rab3A ａnd VAMP2/ Synaptobrevin II receptor PRA. Bassoon may be involved in cytomatrix organization at the site of neurotransmitter release. The gene which encodes bassoon maps to human chromosome 3p21.31. The gene which encodes piccolo maps to human chromosome 7q21.11.Function : May act as a scaffolding protein involved in the organization of synaptic active zones ａnd in synaptic vesicle trafficking.Subunit : Interacts with RABAC1/PRA1, RIMS2 ａnd profilin （By similarity）.Subcellular Location : Cell junction, synapse. Note=Concentrated at the presynaptic side of synaptic junctions.Similarity : Contains 2 C2 domains.Contains 1 PDZ （DHR） domain.