本公司经销KCNG2,心脏钾离子通道蛋白亚基2抗体,克隆类型为polyclonal,宿主来源是Rabbit,KCNG2心脏钾离子通道蛋白亚基2抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
本公司经销KCNG2,心脏钾离子通道蛋白亚基2抗体,克隆类型为polyclonal,宿主来源是Rabbit,KCNG2心脏钾离子通道蛋白亚基2抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
货号:BY-9857R
英文名称:Anti-KCNG2
中文名称:心脏钾离子通道蛋白亚基2抗体
其他名称:名Cardiac potassium channel subunit; KCNG2; KCNG2_HUMAN; KV6.2; Potassium voltage-gated channel subfamily G member 2; Voltage-gated potassium channel subunit Kv6.2.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 51kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
产品介绍:Neuronal and cardiac cells are excited by voltage-gated ion channels. Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. Mutations interfering with potassium ion channels are known to cause a variety of disorders. KCNG2 (potassium voltage-gated channel subfamily G member 2) is also known as voltage-gated potassium channel subunit KV6.2, cardiac potassium channel subunit or KCNF2 and is a 466 amino acid protein. KCNG2 is a multi-pass membrane protein abundantly expressed in heart, liver, skeletal muscle, kidney and pancreas, and detected at lower concentrations in brain, lung and placenta. KCNG2 is an electrically silent subunit that forms heterodimers with KV2.1, creating a unique functional K+ channel. KCNG2-KV2.1 heterodimers are known to be inhibited by tetraethylammonium and propafenone. KCNG2 is thought to downregulate potassium channel currents because KCNG2-KV2.1 heterodimers generate smaller currents than KV2.1 homodimersSubcellular Location : Membrane.Tissue Specificity : Highly expressed in heart, liver, skeletal muscle, kidney and pancreas. Detected at low levels in brain, lung and placenta.