小片段RNA转染专用试剂R4000

产品介绍

英格恩生物公司（ Engreen Biosystem Co,Ltd. ）是专业的 转染试剂研发生产厂商。 Entranster^TMR4000是英格恩生物公司研发合成的针对siRNA、microRNA(miRNA) 、mimic、inhibitor 等小片断RNA的转染试剂。由于纳米技术的应用，Entranster^TM-R4000在细胞转染过程中，表现了的低毒、GX的性能。

应用范围             

专用于siRNA、microRNA(miRNA) mimic、inhibitor等小片断RNA体外转染 。 
 

主要特点

纳米聚合物，特别为RNA转染制造

GX 转染RNA，沉默效率高，可以达到90 ％以上的沉默效率

低细胞毒性，RNAi研究值得应用工具

应用于本产品的文献

1.International Journal of Molecular Medicine . 2018 March 1. MicroRNA-155 inhibits the osteogenic differentiation of mesenchymal stem cells induced by BMP9 via downregulation of BMP signaling pathway.（间充质干细胞成骨细胞分化研究）

2.Journal of Virology . 2018 Feb 14. Lactic acid downregulates viral microRNA to promote Epstein-Barr Virus-immortalized B lymphoblastic cell adhesion ａnd growth.（EB病毒与B淋巴细胞细胞粘附和生长研究）

3.Molecular Medicine Reports. 2018 Feb 13. Long non‑coding RNA BC168687 small interfering RNA reduces high glucose ａnd high free fatty acid‑induced expression of P2X7 receptors in satellite glial cells.（siRNA对高糖和高游离脂肪酸环境下卫星胶纸细胞P2X7受体表达影响研究）

4.BioFactors. 2017 Nov 29. Dihydromyricetin inhibits NLRP3 inflammasome-dependent pyroptosis by activating the Nrf2 signaling pathway in vascular endothelial cells.（二氢杨梅素YZNLRP3炎性体依赖的细胞死亡研究）

5.Experimental Cell Research. 2017 Nov 2. Erythropoietin ameliorates early brain injury after subarachnoid haemorrhage by modulating microglia polarization via the EPOR/JAK2-STAT3 pathway.（siRNA转染小鼠胶质瘤细胞与促红细胞生成素对早期脑损伤作用研究）

6. Journal of Cellular ａnd Molecular Medicine. 2016 Nov 25. A novel P53/POMC/Gαs/SASH1 autoregulatory feedback loop activates mutated SASH1 to cause pathologic hyperpigmentation.（SASH1引起病理性色素沉着研究）

7.Journal of Experimental & Clinical Cancer Research. 2016 Sep 17. Demystifying the mechanistic ａnd functional aspects of p21 gene activation with double-stranded RNAs in human cancer cells.（p21基因激活与人类癌细胞中dsRNA的机制和功能）

8.Journal of Orthopaedic Translation. 2016 May 11. Knockdown of asporin affects transforming growth factor-β1-induced matrix synthesis in human intervertebral annulus cells.（Asporin的敲降可影响人类椎间环细胞中转化生长因子-β1诱导的基质合成）

9. Immunologic Research. 2016 Apr. Upregulation of long noncoding RNA TMEVPG1 enhances T helper type 1 cell response in patients with Sjögren syndrome.（LncRNA-TMEVPG1的上调可增强Sjögren综合征患者T辅助细胞1型细胞反应）

10. Tumour Biol. 2016 Mar. MiR-30a regulates the proliferation, migration, ａnd invasion of human osteosarcoma by targeting Runx2.（MiR-30a通过靶向作用于小家畜相关的转录因子2（Runx2）进而调节人骨肉瘤细胞的增值、迁移及侵袭）